Journal: Nature
Article Title: Autonomous mobile robots for exploratory synthetic chemistry
doi: 10.1038/s41586-024-08173-7
Figure Lengend Snippet: a , Workflow design for autonomous synthesis using mobile robots for sample transport and handling between the ISynth synthesizer and the MS and NMR analysis stations. b , An application-agnostic heuristic reaction planner takes input from the MS and NMR measurements and combines these two orthogonal datasets to plan the next stage in the synthesis experiment. Only reactions that pass predetermined, application-specific thresholds for both the MS and the NMR measurements are deemed to be hits, which are then taken forward for scale-up or for further reproducibility tests (green, pass; orange, fail).
Article Snippet: Apart from the photocatalysis experiments, all synthesis experiments were performed using a Chemspeed ISynth platform.
Techniques: